Research Articles

Peer-reviewed research from PubMed with AI-generated plain-English summaries.

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Showing articles for Lung Cancer (5 total)

Novel CRISPR-Cas9 approach achieves durable remission in treatment-resistant B-cell lymphoma
Lung Cancer Nature Medicine • PMID SEED001
AI Summary

Researchers used CRISPR gene editing to modify patient immune cells, achieving long-term remission in patients who had failed standard chemotherapy. Nine of eighteen patients remained cancer-free at t…
Gut microbiome composition predicts response to checkpoint immunotherapy in metastatic melanoma
Lung Cancer Cell • PMID SEED002
AI Summary

A study of over 260 melanoma patients found that the mix of bacteria in the gut strongly predicts whether immune checkpoint therapy will work, opening the door to microbiome-based treatments to improv…
mRNA vaccine platform demonstrates 87% efficacy against H5N1 avian influenza in phase II trial
Lung Cancer The Lancet • PMID SEED005
AI Summary

Using the same mRNA technology developed for COVID-19 vaccines, researchers achieved 87% protection against bird flu in a clinical trial, with results suggesting the platform could be rapidly adapted …
Multi-omics integration identifies three molecular subtypes of non-small-cell lung cancer with divergent immunotherapy r…
Lung Cancer Nature Cancer • PMID SEED010
AI Summary

A computational integration of three omics layers across nearly 3,000 NSCLC tumours identifies three molecular subtypes that predict checkpoint-immunotherapy response better than current PD-L1 express…
Liquid biopsy ctDNA analysis detects pancreatic adenocarcinoma at stage I with 91% sensitivity
Lung Cancer Nature Biotechnology • PMID SEED006
AI Summary

A blood test that detects fragments of tumor DNA achieved 91% accuracy in identifying early-stage pancreatic cancer, which is notoriously difficult to catch before it spreads and has a five-year survi…