Research Articles
Peer-reviewed research from PubMed with AI-generated plain-English summaries.
Researchers used CRISPR gene editing to modify patient immune cells, achieving long-term remission in patients who had failed standard chemotherapy. Nine of eighteen patients remained cancer-free at t…
Three-year extension data on lecanemab show that the disease-progression-slowing effect seen at 18 months persists out to 36 months, with no new safety signals beyond ARIA rates already documented.…
A study of over 260 melanoma patients found that the mix of bacteria in the gut strongly predicts whether immune checkpoint therapy will work, opening the door to microbiome-based treatments to improv…
By analyzing nearly 100,000 individual brain immune cells, scientists identified twelve distinct subtypes of microglia that behave differently in different brain regions, providing new targets for Alz…
New analysis of a major diabetes drug trial shows that semaglutide protects the heart through mechanisms beyond just weight loss, suggesting the drug has direct cardiovascular benefits that could appl…
Using the same mRNA technology developed for COVID-19 vaccines, researchers achieved 87% protection against bird flu in a clinical trial, with results suggesting the platform could be rapidly adapted …
A computational integration of three omics layers across nearly 3,000 NSCLC tumours identifies three molecular subtypes that predict checkpoint-immunotherapy response better than current PD-L1 express…
A blood test that detects fragments of tumor DNA achieved 91% accuracy in identifying early-stage pancreatic cancer, which is notoriously difficult to catch before it spreads and has a five-year survi…
Scientists showed that the timing of meals — not just how much is eaten — reprograms metabolic gene activity in liver cells, providing a molecular explanation for why intermittent fasting may have hea…
A meta-analysis of nearly 40 long-term studies finds that preserving meniscus tissue during ACL reconstruction substantially reduces the risk of osteoarthritis at 10+ years, even when the meniscal rep…