Blood Flow Restriction Training in the Adolescent Patient: Effects on Muscle Strength and Overall Function Following Anterior Cruciate Ligament Reconstruction Surgery

This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR). The study aims to identify the effect of BFRT on quadriceps muscle strength and the patient's quality of life, and the overall tolerability of BFRT will be examined. Eight physical therapists at four sports medicine physical therapy (PT) sites will oversee all post-operative PT sessions. Subjects allocated to the BFR group will undergo BFRT, while control group will undergo standard-of-care ACLR rehabilitation, 2 days per week for 16 weeks. Measurements of strength, quality of life, and overall function will be completed at regular intervals.

Full record on ClinicalTrials.gov (NCT ID NCT04390035).

Age range: 12–18 · Sex: All · Healthy volunteers: Accepts

Phase

Phase None

Study type

Interventional

Allocation

Randomized

Masking

Open label

Intervention model

Parallel assignment

Primary purpose

Treatment

Enrollment target

120 participants

Started

September 2020

Estimated completion

April 2023

1 site currently enrolling. Representative sites shown below; full site list on ClinicalTrials.gov.