Phase 1 NCT05204836

Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention

University of Calgary · Interventional, Randomized

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Study context Single-site study

Overview

The purpose of this study is to assess if a zoledronic acid injection can alter the trajectory of joint degeneration following an acute anterior cruciate ligament (ACL) injury.

Full record on ClinicalTrials.gov (NCT ID NCT05204836).

Recruitment criteria

Age range: 25–45 · Sex: All · Healthy volunteers: Requires diagnosis

Study design

Phase
Phase 1
Study type
Interventional
Allocation
Randomized
Masking
Single-blind
Intervention model
Parallel assignment
Primary purpose
Treatment
Enrollment target
— participants
Started
May 2023

Outcome measures

Locationsi

1 site participated during the trial period. Representative sites shown below; full historical record on ClinicalTrials.gov.

University of Calgary — Calgary, Alberta (Canada)

Sources

REG
ClinicalTrials.gov — NCT05204836
Trial registry · primary record
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